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Vacuum pump vacuum exhaust _ in the lyophilizer

by:J&T     2020-07-17

how do you determine the vacuum of vacuum pump displacement in the lyophilizer? Below small make up take you to understand it.

( A) Performance of the vacuum pump pumping speed

the lyophilizer vacuum system from atmospheric pressure to 10 pa time not more than 30 min.

( 2) Vacuum pump selection principle

the selected the limits of the main vacuum pump vacuum should be higher than request the limit of the vacuum freeze-drying box 1 ~ 2 orders of magnitude. Medicine freeze-dried general requirements limiting vacuum for 1 ~ 5 pa, selected the main vacuum pump vacuum should be higher than 1 x10 - limit x10 - 1 ~ 1 2Pa。 Rotary vane pumps, slide valve pumps, roots pump, oil pump, are available.

work vacuum freeze-drying box for 4 ~ 4 opa, should be at the top of the main vacuum pump pumping speed pressure range.

the lyophilizer vacuum pump should also use, can smoke in addition to some of the water vapor, or can be adapted to be smoke gas mixed with water vapor.

( 3) Extraction rate calculation

the lyophilizer drainage time requirement for cold trap when sharing a refrigerator and freeze-drying box, this time is very important. Can lead to precool products can't satisfy the melt. If the vacuum condenser ( Cold trap) Refrigeration at the same time, also can keep low temperature cooling, freeze-drying box that demand is not so important. That is to say, may be extended appropriately for time, but it is little influence on the performance of the lyophilizer.

different industry demand of vacuum degree is different, so should choose suitable vacuum pump to meet the needs of the production of vacuum degree requirements.

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