Vacuum freeze-drying machine system maintenance method? _

frozen drying machine ( The lyophilizer) By the refrigeration system, vacuum system, heating system, electrical instrumentation control system. Main components for drying chamber, condenser, refrigeration units, vacuum pump, heating/cooling devices, etc. Freeze drying or freeze-dried, material is the water cut, freeze into solid first, and then make the moisture from the solid sublimate to gas, to remove moisture and ways of preserving material.

vacuum system is one of the important component of the lyophilizer, generally including rotary vane vacuum pumps or dry and roots pump speed vacuum pump. The effect of vacuum system is to build a vacuum to the sublimation of ice manufacturing environment and conditions. The discretion of the vacuum degree of vacuum system directly affect the sublimation rate of products, vacuum system requires its own has lower leakage rate. Vacuum control precision directly affects the pharmaceutical process running. So, the lyophilizer vacuum system how to maintenance and daily maintenance? Below we together and see it!

vacuum system operation is normal voice, if abnormal, please check whether the three-phase electric balance; Vacuum pump to see if there is abnormal vibration, each connection part of the vacuum pump with the pump head whether there is loose phenomenon, if there is, the use of the corresponding fixed measures; With cooling water pump, need enough to keep cooling water flow rate and pressure difference, can touch during the operation of the pump body temperature; Nitrogen purging pump, need to keep nitrogen have enough flow and pressure; Need to check whether the oil level is kept in normal oil level, below the normal oil level to be in a timely manner to fill and stipulated by the vacuum pump oil. If the vacuum pump oil emulsification, need to open the gas ballast valve run 2 hours; True if the vacuum pump oil discoloration, timely replace vacuum pump oil, and cleaning filter, and replace the filter; Observe whether the vacuum pump oil, such as the oil timely maintenance downtime.

if you don't use pump over a period of time, should shut off the power and cooling water supply; If the pump directly closed at the end of the freeze-drying process, water vapor may be remaining in the pump body. If the pump is closed for a long time, the mechanical structure of the pump, the liquid may be corrosion may be the cause of the pump can't start again. Suggest pump at the end of the debugging idling about half an hour.

pump in the vacuum pump is open and electricity, power vacuum pump stops. Electric pump head valve whether can judge from the end of a valve inlet. The muffler is removed, by hand to block air inlet, sucked the proof valve have spirit to have no electricity, whereas electricity; Close vacuum pump valve power supply cut off pump, through the change of silicon tube vacuum tube to determine the pump head valve is closed tightly.

in the outlet connection, a suitable pipe at the inlet connection a proper return pipe; Open the feed line to provide clean water, reverse flushing cooling jacket, the sediment rinse as far as possible; Let water flow for a few minutes, then turn off the water, and then disconnect the return pipe.

unscrewed the oil discharge valve and the old oil in the tank up to vacuum pump automatically flow to the screw nut oil position let oil flow out. After the old oil is put, from the vacuum pump oil injection of a small amount of clean vacuum pump oil ( 100~500mL) , flush internal vacuum pump cavity. Then start the vacuum pump running around 1 min, close vacuum pump, oil will inject new release, if still not make the oil release should continue to inject new oil flushing, until clean. Then, tighten the oil discharge valve, gas cap unscrewing lubrication, into the vacuum pump to join the new vacuum pump oil, the oil level of oil line, spin on gas cap again;

put container drain mouth below, spin down oil mouth screw. Close the bleeding point, at the same time open vacuum pump, open the gas ballast valve cover part of the vacuum pump and exhaust outlet, to produce an adequate internal pressure, the dirty oil out very quickly, and then according to the above steps step 1 wash inside the vacuum pump cavity, a new oil.